Aptamer Selection
Selection of aptamers for whole cells, bacteria, fungi, tissues or proteins in vitro or in vivo for pathologic or healthy organs/tissues in the organism of experimental mice
Aptamer Selection, Characterization, 3D Structure Simulation And Target Identification
SENSITIVITY AND SPECIFICITY OF THE SELECTED APTAMERS IS AT LEAST 85%
WE USE INDIVIDUAL SELECTION TACTICS FOR EACH TARGET
100% EFFICIENCY OF the SELECTED APTAMERS FOR DIAGNOSTICS AND THERAPY
Selection of aptamers for whole cells, bacteria, fungi, tissues or proteins in vitro or in vivo for pathologic or healthy organs/tissues in the organism of experimental mice
Mathematical analysis of sequenced aptamer pools after the Next Generation Sequencing which allows us to choose leading sequences and to estimate the enrichment of aptamers during selection
Estimation of affinity, specificity and dissociation constant of synthetic aptamers using flow cytometry and laser scanning microscopy
Definition of the of aptamer tertiary structure in buffer using Small Angle X-ray Scattering with the following molecular design
Protein target identification using Aptamer-facilitated Biomarker Discovery technique and mass-spectrometry analysis with the following target verification by concurrent antibody replacement and co-staining
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